The use of enzyme-mediated reactions has transcended ancient food production to the laboratory synthesis of complex molecules. This evolution has been accelerated by developments in sequencing and DNA synthesis technology, bioinformatic and protein engineering tools, and the increasingly interdisciplinary nature of scientific research. Biocatalysis has become an indispensable tool applied in academic and industrial spheres, enabling synthetic strategies that leverage the exquisite selectivity of enzymes to access target molecules. Anticipated this trend many years ago, we outline the technological advances that have led to the field’s current state. Integration of biocatalysis into mainstream synthetic chemistry hinges on increased access to well-characterized enzymes and the permeation of biocatalysis into retrosynthetic logic. Ultimately, we managed to level up the synthesis of increasingly complex molecules at new levels of efficiency and throughput.

• Biodegradable and environmental friendly reagents and solvents
• Services and consultation tailored to specific development needs
• Efficient synthetic and processing routes
• Decreased cost and turnaround time through minimization of side reactions, by-products and impurities
• Optimization and enhancement of conversion rates, yields, and selectivity
• Design and setup of self-regenerating or low-maintenance systems